Design, synthesis and biological evaluation of Piperazinylanthranilamides as potential factor Xa inhibitors
AN Khadse, HH Savsani, RV Chikhale… - Journal of Molecular …, 2022 - Elsevier
… phenylpiperazinylamides were used as S4 binding ligands to improve the … they displayed
excellent anti-FXa potency with weak CYP3A4 inhibitory … Structure-activity relationship studies …
excellent anti-FXa potency with weak CYP3A4 inhibitory … Structure-activity relationship studies …
Design and Synthesis of Some Novel Heterocyclic Compounds as Potential Antithrombotic Agents
KA Nivrutti - 2021 - search.proquest.com
… of factor Xa inhibitors in the antithrombotic therapy, we have taken rivaroxaban (15) and
anthranilamide based … to develop small, orally active enzyme inhibitors.Though FXa possesses …
anthranilamide based … to develop small, orally active enzyme inhibitors.Though FXa possesses …
Silver-mediated Room Temperature Reactions for the Synthesis of N-α-Ketoacyl Sulfoximines and N-α,β-Unsaturated Acyl Sulfoximines
… Our group has a persistent interest in the functionalization … a novel synthetic methodology
has been developed for C–N bond formation and for the synthesis of N-α-ketoacyl sulfoximines …
has been developed for C–N bond formation and for the synthesis of N-α-ketoacyl sulfoximines …
Visible-Light-Induced N-Acylation of Sulfoximines
P Qiu, X Duan, M Li, Y Zheng, W Song - Organic Letters, 2022 - ACS Publications
… developed a novel visible-light-induced N-acylation of sulfoximines under metal-, base-, and
… It could be further utilized to synthesize α-keto N-acyl sulfoximines and modify amino acids …
… It could be further utilized to synthesize α-keto N-acyl sulfoximines and modify amino acids …
Design and Synthesis of Some Novel Heterocyclic Compounds for Antithrombotic Activity
NR Patel - 2020 - search.proquest.com
… groups to develop orally active selective FXa inhibitors. 2.3.1… -based Factor Xa Inhibitors
Designing aspects, synthesis, … biological profile of anthranilamide based FXa inhibitors, we …
Designing aspects, synthesis, … biological profile of anthranilamide based FXa inhibitors, we …